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Throughout the process of pyroptosis, caspase 1 is responsible for cell swelling (Fink and Cookson, 2006), DNA fragmentation (Shao et al., 2007), and other related functions (Figure 3)

Intranasal insulin therapy for Alzheimer disease and amnestic mild cognitive impairment: a pilot clinical trial

Furthermore, FMO3 has been shown to serve as a central regulator of tissue cholesterol balance and to be involved in insulin resistance and dyslipidemic changes in mouse models, suggesting the FMO3 and TMAO pathway as potential mediators of diabetes associated atherosclerosis 52,53

Thymosin Beta-4 enhances cells' ability responding to these electric signals improving migration directionality